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When ultrapure and high-purity water processes depend on reliable TOC values, precision is paramount.
Our miniTOC and miniTOC² TOC analyzers operate on the principle of proven UV oxidation and differential conductivity – the established method for reliable trace TOC analysis in ultrapure water. This technology combines fast, robust measurement with standards-compliant documentation (including USP <643>, EP 2.2.44) – developed and manufactured in Germany.
These TOC analyzers are used in a wide range of applications. Whether online monitoring in a loop, offline single-sample analysis, or a multi-channel setup: you receive a solution that integrates seamlessly into your processes. The modular concept extends beyond hardware components to include software modules such as optional CFR 21 Part 11 functionality.
For over three decades, membraPure has been an expert in laboratory water purification, with development and manufacturing based in Germany.
Durable components and low maintenance requirements sustainably reduce your overall costs.
Thanks to the large touchscreen and clear icon language, our systems are easy to operate.
The modular design makes it possible to choose only the components that are actually needed – for maximum user-friendliness at minimum cost.
A TOC analyzer measures the total organic carbon content in water by oxidizing the sample. membraPure’s TOC analyzers utilize UV ​​light oxidation, which then affects the conductivity of the sample.
The TOC value is determined from the difference in conductivity before and after oxidation. This flow-through method is very suitable for continuous online monitoring and the analysis of individual samples and is therefore widely used.
TOC is the key indicator for organic contaminants in pure and ultrapure water; its monitoring ensures stable processes and compliance with pharmacopoeia requirements (e.g., USP <643>, EP 2.2.44).
Rising TOC levels indicate the formation of biofilms, which cause organic fouling within the water purification system, thereby stressing and damaging components, shortening their lifespan, and leading to a failure to meet the required water quality standards.
The miniTOC² is the advanced successor to our miniTOC, which has proven itself worldwide for many years and is widely used by many customers. To determine the suitable system with the appropriate device configuration, we will clarify a few key questions with you:
Please fill out your questionnaire and send it back to us. We will contact you immediately!
Experience that builds trust: Since 2009, TOC analyzers have been part of membraPure’s portfolio alongside our ultrapure water systems. Thanks to continuous development and production in Germany, as well as valuable feedback from customers and partners, we have been creating new systems with expanded and improved features ever since.
Consistently focused on optimizing laboratory processes: Over 30 device configurations as ready-to-connect tabletop, under-counter or wall-mounted units ensure maximum flexibility in terms of practical use, price and planning.
Globally connected, locally supported: With over 30 international partners, membraPure guarantees worldwide support international partners – in person and very often in the respective local language.
Climate-neutral production: Since 2021, membraPure has been a climate-neutral company thanks to emissions offsetting – a clear commitment to responsibility and sustainable business practices.
For PW/WFI loops and QC/QA, TOC monitoring ensures release quality in accordance with pharmacopoeias (USP <643>, EP 2.2.4).
In ultrapure water systems used in semiconductor manufacturing, TOC serves as an early warning parameter against organic fouling and process disruptions.
TOC for the early detection of organic contaminants and leaks in feedwater for cooling water circuits, boiler feed and condensate return.
Made in Germany – Quality that lasts
Since 2009, we at membraPure have been developing TOC analyzers – always with the aim of combining precision, reliability, and user-friendliness. Developed and manufactured in Hennigsdorf near Berlin, our devices represent German engineering, the highest quality, and long-term cost-effectiveness. Regular testing of our raw materials and development processes ensures consistently high product quality. This increases reliability and lifespan while reducing maintenance requirements. For users, this means a long-term reduction in operating costs. Did you know? Products manufactured in Germany typically have a service life that is up to 35% longer.
Perfectly tailored to your analysis requirements
Our TOC analyzers feature a modular design and can be configured specifically for your application. The miniTOC and miniTOC² TOC analyzers are ideally suited for TOC monitoring of pure and ultrapure water as well as WFI (Water for Injection) in industries such as pharmaceuticals, power plants & energy, semiconductor manufacturing, and large-scale water treatment plants in general.
Intelligent technology down to the last detail
What distinguishes our TOC analyzers is not only precise measurements, but also intelligent solutions in every detail. Since the first TOC analyzer in 2009, the systems have been continuously improved.
From the proven basic model miniTOC to the current miniTOC². With an innovative UV reactor, increased oxidation performance, reduced sample consumption, and an optional autosampler with increased sample capacity, they offer the right equipment for every application.
Whether it’s the intuitive touch display, flexible data export options, or service features that simplify operation, every detail is designed to streamline processes, make efficient use of laboratory time, and provide optimal support for the user.
Support that goes the extra mile
A TOC analyzer is only as good as the support behind it. membraPure supports users worldwide with personalized service, customized training, and comprehensive resources – directly or through certified distribution partners.
We offer various model variants.
Analyze pure and ultrapure water with our TOC analyzers.
Both the miniTOC and the miniTOC² follow a modular design. Starting from a basic system, the devices can be configured with one (basic) or up to three measuring points (pro).
Depending on the application, they can be flexibly expanded with additional hardware options such as analog outputs, trigger input, or input pressure monitoring. Software functions such as 21CFR Part 11 compliance, offline mode, or multiline mode are also available.
This results in an individual solution for each laboratory, optimally tailored to the requirements and offering a balanced cost-benefit ratio.
The hardware and software options that differentiate the functions can be found directly on the respective product pages of the miniTOC and miniTOC² TOC analyzers.
| Hardware/Software/Accesories | miniTOC | miniTOC² |
|---|---|---|
| Application of pure and ultra pure water | yes | yes |
| Standards DIN EN 1484, USP 643, E.P. 2.2.44 | yes | yes |
| Configuration basic/ pro | yes | yes |
| Detection range | 0.5 - 1000 ppb | 0.5 - 1500 ppb |
| Detection limit | 0.1 ppb | 0.009 ppb (adapted to ICH(Q2) R1 |
| Detection method | conductivity | conductivity |
| Oxidation method | UV reactor with integrated UV lamp | UV reactor with glass spiral guide and replaceable UV lamp |
| Conductivity range | up to 10 µS/cm | up to 10 µS/cm |
| Consumption | 14 mL/min | 7 mL/min |
| IP 54 | optional | yes |
| 2-pump configuration (dual mode) | optional | optional |
| Analog outputs | optional | optional |
| 21 CFR part 11 Software | optional | optional |
| Individual measurements | optional | optional |
| Accessories (pressure reducers, heat exchangers) | optional | optional |
| Standards (USP traceable) | optional | optional |
| IQOQPQ Documents and validation possible | yes | yes |
| Autosampler | 15 positions with a sample volume of 100 mL each | maximum of 80 positions with a sample volume of 40 mL each |
| UV lamp replacement | 6-9 months | 12 months |
A TOC analyzer is only as good as the support behind it.
Our TOC analyzers are distinguished in particular by their low operating costs and minimal maintenance requirements due to fewer components. The latter can even be performed by the customer themselves.
We offer our customers in Germany, Austria, Switzerland, and neighboring countries such as Belgium, installation, setup, and training as a service. This service can also include validation (IQOQ) if desired.
Furthermore, membraPure supports users worldwide with personalized service, customized training, and comprehensive resources, all delivered through qualified sales partners.
We would be happy to assist you in choosing the right TOC analyzer and
to answer any questions you may have regarding your required configuration.
A TOC analyzer measures the total organic carbon in water. membraPure systems use UV oxidation as the digestion method and differential conductivity as the detection method to reliably determine TOC levels in pure and ultrapure water. This is primarily done in online mode, i.e., continuous 24/7 measurement, but can also be performed for individual samples.
Typical areas of application include pharmaceuticals & biopharmaceuticals (PW/WFI), the semiconductor industry, power plants & energy, and large-scale water treatment plants.
TOC is a key indicator of organic contamination. The TOC analyzer uses a long-established method for reliable trace TOC analysis in pure and ultrapure water. Continuous monitoring provides an indirect indication of the presence of organic compounds, which may, for example, be due to biofilm formation. TOC monitoring allows for timely implementation of countermeasures, thus protecting system components and ensuring compliance with pharmacopoeia requirements (USP <643>, EP 2.2.44).
Our devices comply with the standards and norms USP <643>, EP 2.2.44 and support optional 21 CFR Part 11 functions for compliant documentation, if required.
The miniTOC² is the consistently further developed generation of our proven miniTOC. It offers an extended measuring range up to 1500 ppb, a robust, IP54-protected industrial PC as standard, and a newly designed UV reactor geometry that ensures even more efficient oxidation with a longer UV lamp lifespan. At the same time, the miniTOC² significantly reduces sample consumption, saving costs and resources. With an optional autosampler for higher sample capacity and improved software with extended evaluation and documentation functions, it meets the latest requirements for laboratory routine and compliance.
Continuous flow measurement enables fast online monitoring within seconds. This technique is widely used and has been proven over many years in TOC analyzers and is also suitable for individual sample analyses.
The miniTOC and miniTOC² TOC analyzers have a modular design. The systems consist of a basic housing that can be expanded with suitable options depending on the application, such as multiple measuring inputs, analog outputs, 21CFRPart11 software, autosampler, or special configurations such as trigger input and inlet pressure monitoring. This provides each user with a customized solution that optimally meets their requirements while offering a balanced cost-benefit ratio.
The devices are designed for quick plug-and-play installation. In Germany, Austria, Switzerland, and neighboring countries, membraPure also offers installation, training, and optional validation (IQ/OQ/PQ).
Our systems reliably measure TOC in pure water, ultrapure water, and WFI (Water for Injection).
Yes, the devices can be integrated directly into ultrapure water loops or operated as a stand-alone solution. They are also suitable for subsequent integration into existing systems and do not have to be installed directly when the water treatment plants are commissioned.
Thanks to long-lasting components, the maintenance requirements for the TOC analyzers are low. UV lamps have a lifespan of 12 months or more with proper use. The pump hoses should be replaced after 6 months of continuous operation. However, the "dual pump head" option halves the load on a single pump hose, so that replacement is only necessary after 12 months, ideally at the same time as the UV lamp. This means that calibration and SST only need to be performed once a year.
Yes, we certainly offer this option. With a maintenance contract, you will be reminded of upcoming maintenance in advance and receive preferential scheduling compared to customers without a contract. In addition, you benefit from more attractive terms and predictable service quality.
Consumables and spare parts are usually ready for dispatch within 48 hours.
In this case, you can contact our service team by phone or email. If we cannot help you remotely, we will try to send a service technician to your location as quickly as possible, provided you are located in a German-speaking country. For customers abroad, our local partners will be happy to assist you.