Precise Amino Acid Analyzers for the use in clinical laboratories

Determine amino acids for newborn screening, food and beverages and more

Our ARACUS systems deliver outstanding results for amino acid analysis in research. They work according to the gold standard of post column derivatization with ninhydrin, using maintenance free LED photometers. A separation of up to 44 amino acids in about one hour is possible. The ARACUS is available in 3 versions, suitable for your field of application.

TESTIMONIALS

Excellent system. Software is manageable. Support is outstanding. We use the instrument in a clinical diagnostic laboratory and have found it to be very reliable, requiring little maintenance. We do have some issues getting consumables into the US."

"We have been determining the free amino acids in plant samples with the ARACUS amino acid analyzer since 2010. From the beginning, we were won over by the very good service provided by the team from membraPure. The high accuracy and reproducibility of the measurement results should be emphasized, which is an advantage for long-term monitoring studies. The system works reliably and the provision of ready-made solutions and standards means that the amino acid analyzer is extremely user-friendly. Due to the fully automatic and time-efficient operation of the device, the determination of the amino acids is also very suitable for numerically extensive sample series."

"It's so convenient and user-friendly. I really like to use this equipment. The results fit well with our recipes."

"Replaced our 20 year old BioChrom30. Uses much less reagent and has nearly identical performance. Software is easy to use. Support has been excellent. Highly recommended."

"This analyzer is easy to use in terms of sample preparation, sample run as well as data analysis. The results are reproducible. However, we did run into several problems, such as SD card fault, pump fault, unstable pressure. The service team and engineer helped resolve the problems every time. In general I'm satisfied with their product and service. It would be better if there were local service support so that we do not have to go back and forth with Germany all the time."

Reliable analysis results for a wide range of applications

Qualitative and quantitative analysis of amino acids is required for a wide range of applications. Our ARACUS systems are designed for use in clinics, quality control, the pharmaceutical and food industry as well as in research. The ARACUS AA analyzers use the most precise and reproducable methodology, with which you can get up to 44 AA with an “Retention time reproducibility (RSD)” of less than 0.1%. Choose your desired configuration with the aracus lite, classic and advanced – depending on the complexity of your amino acid analyses.

Amino Acid Analyzers for all major lab applications

Detectors with maintenance-free LED technology (440 & 570 nm) / no UV/VIS lamp degeneration and lamp exchange
Chloride-free and citrate-free buffer system / less aggressive to the components of the liquid handling tubes, fittings and connection
Small eluent consumption / about 200 µL/min in analysis mode
High sensitivity of amino acids / choice of two sensitivity detector levels
Level sensors for eluents / warn the user if needed fluidic volume is too low for planned analysis
Easy access to all components of the entire system

MODELS

ARACUS Lite

Simplified configuration of the ARACUS „classic“ for a reduced number of samples and smaller budget

ARACUS Classic

Standard configuration of the series, allows the continous analysis of 96 samples in a cooled autosampler

ARACUS Advanced

Extended configuration by an additional second pump drive. Allows the independent operation of two fluidic lines

APPLICATIONS

Wide range of applications for our Amino Acid Analyzers

Our instruments are able to provide analytical results in various fields of application. The most common areas of application for the determination of amino acid analyses are shown below.

Determination of free/ physiological amino acids in blood plasma, serum, salvia and urine

Newborn screening
Argininemia (ARG)
Arginosuccinic aciduria (ASA)
Citrullinemia (CIT)
Homocystinuria (HCY)
Maple syrup urine disease (MSUD)
Phenylketonuria (PKU)
Ornithine transcarbamylase deficiency (OTC)
Tyrosinemia (TYR)

Determination of hydrolysed amino acids in food, beverages and feedstuff
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Determination of biogenic amine for the investigation of metabolic processes

APPLICATION NOTES

Be inspired with our example applications

Find out whether the manufacturer’s specifications for sports nutrition are correct or determine the gelantine added to ham? Our analysis application examples for the determination of amino acids help to better understand the field of application of our amino acid analyzers.

On our overview page, you will find downloadable application notes, some of which we have created together with institutions and facilities.

LITERATURE

Widely used in research and science

In our literature list you will find an overview of all links to publications in which our ARACUS models were used.

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FAQ

WHERE IS AMINO ACID ANALYSIS USED?

Amino acid analysis is used wherever the content of free/ physiological or protein-bound amino acids has to be determined. The fields of application range from diagnostics to quality control and research. Sample matrices are usually:

- blood plasma, blood serum
- saliva, urine
- spinal fluid
- Food, beverages
- animal feed

WHY IS A SPECIAL INSTRUMENT NEEDED FOR AMINO ACID ANALYSIS?

In the amino acid analyzer, ion exchange chromatography is combined with the HPLC technique. Samples are usually very complex in nature and amino acids, even ionic compounds without a specific absorption wavelength, are difficult to analyze using conventional HPLC methods. The combination of both techniques compensates for the disadvantages. Already due to extensive testing, further method developments are very short. This allows the user to routinely operate the system with little user intervention and ensures high sample throughput.

WHERE IS AMINO ACID ANALYSIS USED?

- blood plasma, blood serum

- saliva, urine

- spinal fluid

- Food, beverages

- animal feed

Precise Amino Acid Analyzers for the use in clinical laboratories

Determine amino acids for newborn screening, food and beverages and more

TESTIMONIALS

FEATURES of our Amino Acid Analyzers

Reliable analysis results for a wide range of applications