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uniTOC Analyzer

TOC Analysis from Ground Water to Ultra Pure Water


Fang ZheSinograin Oils and Grains Co, Ltd, China
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"uniTOC has two powerful injection ports. Built-in computer to save purchasing cost. Has dual channel self-regenerating carbon dioxide filters, saving gas use and cost. High efficiency ultraviolet lamp. Short analysis time.
Hu XiaoqiangVellpharma company, China
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The result is ok. Running normally since installation
Wang LihuaIntertek, China
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uniTOC has two powerful injection ports. Built-in computer to save purchasing cost. Two-channel self-regenerative carbon dioxide filter, with dual channel self-regeneration carbon dioxide filter. Saves gas use cost. High efficiency ultraviolet lamp and short analysis time.


Designed for Total Organic Carbon Analysis of Ground Water and Ultrapure Water

  • The uniTOC device uses the full oxidation by UV. The oxidation process can be enhanced with additional dosage of reagent (persulfate)
  • By using the NDIR detector the uniTOC gives precise results in applications of ground water to ultra pure water. 
  • The NDIR detector is absolutely selective to carbon dioxide and therefore independent from conductivity and sample temperature. 
  • Measuring times are short and the continuous self-cleaning of the reactor avoids any cross-contamination. 
  • Since the quality of the stripped gas can be low, the use of pressurised air in combination with our air filters saves money and is optionally available.
  • Calibration and SST of the uniTOC is easy and can be done by the user. 
  • Online operation is interrupted briefly for the system checks to be performed. 
  • The operator simply has to connect the inlet with the calibration standard solutions and the diluting water sample. 
  • The software enables the user to perform calibration and SST independently and the programmable sequence ensures the automatic procedure and data evaluation of the test. 
  • The verification of the TOC results according to the requirements of USP and Ph.Eur is realised by the periodic performance of system suitability tests.

Main technical specifications of the system


The scheme shows the principle of uniTOC with to different pathways for TIC and TOC and the principle of measuring the TOC value.

Flowchart: uniTOC
Options: Pressure Regulator miniTOC

Pressure regulator for medium

If the feed pressure is higher than 1.5 bar a pressure transducer is required.

Options: IQQ Documents Aquinity P10

IQ/OQ documents

Validation documents IQ/OQ for uniTOC.

Options: Air Filtration miniTOC

Air filtration unit

To use compressed air instead of oxygen or nitrogen.

Options: Heat exchanger miniTOC

Heat exchanger

Keeps the temperature below 50 °C degrees.

Technical Specifications
method & detectionUV oxidation & NDIR (enhanced oxidation; configurable with reagent)
sample volume20 mL loop (low range), 5 mL loop (high range)
period of measurement6 to 15 min
measurement range2 to 5000 ppb (low range), 15 ppb to 20 ppm (high range)
detection accuracy~3 ppb or 2 % (whatever is greater)
ports2 for samples | 1 for reagent
related normsUSP <643>, DIN 32645, EP 2.2.44, DIN EN 1484, CFR 21 part 11, IP 45
ambient parametersrelative humidity: 10 to 95 %, temperature: 10 to 45 °C
interface portsanalog (4 - 20 mA)
dimensions, weight, power400 x 300 x 600 mm, 24 kg, 110 - 230 V, 50 Hz, 70 to 105 Watt
Medium Requirements
type of sample mediumfrom ground water to ultra pure water
sample temperature10 to 50 °C
inlet pressure< 1.5 bar
compressed gasair, oxygen, nitrogen | free of carbon dioxide
inlet pressure of gasnitrogen: 1 to 1.5 bar | oxygen: 3.5 to 5 bar


The uniTOC is used for basic to ultra pure water applications (e.g. WFI - water for injection).

The uniTOC operates according to USP 643, DIN EN 1494, DIN32645 as well as EP 2.2.44.

The uniTOC is only suitable for liquid media such as ground, pure and ultrapure water, but not waste water or solids.

The uniTOC covers a TOC range from 2 ppb to 5000 ppb, but can cover a range from 15 ppb to 20 ppm in a so-called "high range" configuration. For higher concentration ranges, the addition of oxidation support reagent is recommended.

The uniTOC is independent of conductivity values, but it is not recommended to use it with solutions with a high salt content (e.g. seawater), as crystallization processes can clog the fluidics and even occupy them.

The uniTOC uses classical oxidation by means of UV radiation. The resulting carbon dioxide is then determined via a selective NDIR detector and the TOC value is thus determined.

The uniTOC is a classic online monitoring system, but can also be used in offline mode for measuring individual samples.

Yes, the uniTOC can be calibrated easily and intuitively under the user's guidance. In addition, the "low range" variant has an SST (system sustainibility test) function.

In addition to the calibration solutions, the pump hose must be changed at regular intervals and a new UV reactor inserted. After a subsequent calibration, the system is ready for use again.

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