flexiTOC2

flexiTOC Analyzer

The next generation TOC analyzer for Tap Water to Ultra Pure Water

The flexiTOC is a high-sensitivity Total Organic Carbon (TOC) analyzer designed for tap water to ultra pure water applications. The analytical method is based on UV oxidation of organic carbon compounds in aqueous samples to carbon dioxide (CO₂). The generated CO₂ is quantified using a highly sensitive NDIR detector, ensuring excellent detection limits and measurement stability. The system supports reagent-free operation for TOC levels below 2000 ppb and operation with reagent for higher TOC concen-trations and less oxidative substances, depending on the application.

TESTIMONIALS

Fang ZheSinograin Oils and Grains Co, Ltd, China
"uniTOC has two powerful injection ports. Built-in computer to save purchasing cost. Has dual channel self-regenerating carbon dioxide filters, saving gas use and cost. High efficiency ultraviolet lamp. Short analysis time.
Hu XiaoqiangVellpharma company, China
The result is ok. Running normally since installation
Wang LihuaIntertek, China
uniTOC has two powerful injection ports. Built-in computer to save purchasing cost. Two-channel self-regenerative carbon dioxide filter, with dual channel self-regeneration carbon dioxide filter. Saves gas use cost. High efficiency ultraviolet lamp and short analysis time.

OVERVIEW

Designed for Total Organic Carbon Analysis of Ground Water and Ultrapure Water

  • The uniTOC device uses the full oxidation by UV. The oxidation process can be enhanced with additional dosage of reagent (persulfate)
  • By using the NDIR detector the uniTOC gives precise results in applications of ground water to ultra pure water. 
  • The NDIR detector is absolutely selective to carbon dioxide and therefore independent from conductivity and sample temperature. 
  • Measuring times are short and the continuous self-cleaning of the reactor avoids any cross-contamination. 
  • Since the quality of the stripped gas can be low, the use of pressurised air in combination with our air filters saves money and is optionally available.
  • Calibration and SST of the uniTOC is easy and can be done by the user. 
  • Online operation is interrupted briefly for the system checks to be performed. 
  • The operator simply has to connect the inlet with the calibration standard solutions and the diluting water sample. 
  • The software enables the user to perform calibration and SST independently and the programmable sequence ensures the automatic procedure and data evaluation of the test. 
  • The verification of the TOC results according to the requirements of USP and Ph.Eur is realised by the periodic performance of system suitability tests.

Main technical specifications of the system

Flowchart

The scheme shows the principle of flexiTOC.

flexiTOC Fließschema

Options & Features

Multiline Mode

The flexiTOC pro is providing 4 different inlets. The additional software upgrade allows the user to measure up to 3 loops sequentially, and configure the duration of each interval measurement separately.

Sample mode

A sample mode configuration is available, and used to measure separate samples offline. This sequence can be customized by the user.

Enhanced hardware performance

Optimized UV reactor geometry and harmonized gas flow maximize oxidation efficiency, supported by continuous monitoring.

Check of sample flow

Initiates alarm in case of inlet flow equal zero, in combination with pressure sensor.

Data export

Measurement data can be exported to an external storage device in various formats. Additionally, data can be stored in the cloud via a network connection, and if necessary, shared with customer service for error diagnosis.

Heat exchanger & Pressure regulator

A heat exchanger is required for medium temperatures above 50 °C, while a pressure transducer is required if the incoming medium pressure exceeds 0.5 bar.

System status

A complete software overhaul delivers a detailed status overview, presenting general information about the device’s status in a clear and concise manner. This includes operating hours for individual sensors, a pump, and the UV lamp.

IP54

The screen and the fan of the flexiTOC is supplied with IP54 protection as standard. The housing protects the flexiTOC from dust deposits and water jets.

Calibration & System Verification Options

Enables reagent and water blank determination as well as multipoint calibration with internal standard dilution for enhanced analytical accuracy.

21 CFR part 11 software

Software with 21 CFR part 11 conformity for pharma applications ensures secure data handling, electronic records and electronic signatures.

Technical Specifications & Requirements

method & detection

type of sample

sample volume

period of measurement

measurement range

detection accuracy

ports

related norms

ambient parameters

interface ports

carrier gas

inlet pressure & temperature

UV oxidation with CO₂ detection (NDIR)

tap to ultra pure water

5 – 30 mL reagent or dilution water is added automatically

Sample interval 5 -10 min, user defined interruptions up to 24h

0.05 to 20 ppm, up to 100 ppm in diluting mode

< 500 ppb ± 5 ppb, > 500 ppb ± 1 % within non diluting mode

1 for sample, 1 for dilution water, 1 for reagent | 1 for sample, 3 for SST

USP <643>, EP 2.2.44, DIN EN 1484

relative humidity: 10 to 95 %, temperature: 10 to 45 °C

analog (0 – 20 mA), according to Namur NE43

N2, O2, compressed air, gas pressure: 1 – 4 bar, consumption: approx. 12 L/h

< 0.5 bar (> 0.5 bar pressure reducer is needed) & 50 °C

Technical Specifications
method & detectionUV oxidation & NDIR (enhanced oxidation; configurable with reagent)
sample volume20 mL loop (low range), 5 mL loop (high range)
period of measurement6 to 15 min
measurement range2 to 5000 ppb (low range), 15 ppb to 20 ppm (high range)
detection accuracy~3 ppb or 2 % (whatever is greater)
ports2 for samples | 1 for reagent
related normsUSP <643>, DIN 32645, EP 2.2.44, DIN EN 1484, CFR 21 part 11, IP 45
ambient parametersrelative humidity: 10 to 95 %, temperature: 10 to 45 °C
interface portsanalog (4 - 20 mA)
dimensions, weight, power400 x 300 x 600 mm, 24 kg, 110 - 230 V, 50 Hz, 70 to 105 Watt
Medium Requirements
type of sample mediumfrom ground water to ultra pure water
sample temperature10 to 50 °C
inlet pressure< 1.5 bar
compressed gasair, oxygen, nitrogen | free of carbon dioxide
inlet pressure of gasnitrogen: 1 to 1.5 bar | oxygen: 3.5 to 5 bar

FAQ

The uniTOC is used for basic to ultra pure water applications (e.g. WFI - water for injection).

The uniTOC operates according to USP 643, DIN EN 1494, DIN32645 as well as EP 2.2.44.

The uniTOC is only suitable for liquid media such as ground, pure and ultrapure water, but not waste water or solids.

The uniTOC covers a TOC range from 2 ppb to 5000 ppb, but can cover a range from 15 ppb to 20 ppm in a so-called "high range" configuration. For higher concentration ranges, the addition of oxidation support reagent is recommended.

The uniTOC is independent of conductivity values, but it is not recommended to use it with solutions with a high salt content (e.g. seawater), as crystallization processes can clog the fluidics and even occupy them.

The uniTOC uses classical oxidation by means of UV radiation. The resulting carbon dioxide is then determined via a selective NDIR detector and the TOC value is thus determined.

The uniTOC is a classic online monitoring system, but can also be used in offline mode for measuring individual samples.

Yes, the uniTOC can be calibrated easily and intuitively under the user's guidance. In addition, the "low range" variant has an SST (system sustainibility test) function.

In addition to the calibration solutions, the pump hose must be changed at regular intervals and a new UV reactor inserted. After a subsequent calibration, the system is ready for use again.

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Analysis of the amino acid composition of cell culture media
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