Discover the Applications of the
Ion Chromatograph IONUS

This collection showcases a range of applications developed
by the membraPure IC Applications Lab

Further collaborations were created with valued customers and research institutions. We’re constantly innovating and expanding the capabilities of the IONUS. If you have a specific analytical challenge, we invite you to contact our sales team at sales@membrapure.de. We’re eager to partner with you in developing new applications of value for you on the IONUS.

 

Perform rapid and accurate determinations of anions, cations, organic acids, and transition
metals
with the membraPure IONUS Ion Chromatograph.

This versatile system is designed for applications in research, development, quality control, process control, and routine analysis, offering exceptional performance for aqueous solutions, foods, beverages, chemical components such as amines, and environmentally relevant water investigations.

This introduction highlights the key features of the IONUS system: speed, reliability, and versatility. In the field of Ion Analysis, the IONUS brings applicability to various analytical needs. When you consider IC, and the IONUS specifically, think:

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Ease of Use

Simplify your ion chromatography workflow with the user-friendly IONUS

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Compatibility

The IONUS seamlessly integrates with IC columns and eluents from all major manufacturers

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Specific Applications

Ensure compliance with regulations like EPA 300.0 for anion analysis in drinking water

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Quality Control

The IONUS is ideal for the soda beverage industry for the analysis of bromate

Unleash the Power of Ion Analysis: The
membraPure IONUS Ion Chromatograph

The membraPure IONUS Ion Chromatograph streamlines your analytical workflow, eliminating the complexities often associated with ion chromatography.

Designed to be user-friendly, the IONUS requires minimal training, keeping operational costs low. Furthermore, its robust design minimizes maintenance needs, thus improving performance, reliability, and the best ROI in the industry.

Most importantly, the IONUS unlocks a vast array of applications, empowering you in research, environmental monitoring, quality control, and various other fields.

From analyzing food and beverage samples to ensuring water purity, the IONUS delivers exceptional performance across diverse analytical demands.

Ion Chromatography: A Versatile Workhorse for Diverse Markets

on Chromatography (IC) shines with its remarkable application diversity. It’s a powerful analytical tool used across numerous markets, from environmental monitoring (ensuring water quality), and food safety (identifying contaminants) to health supplement analysis (guaranteeing purity) and industrial process control (optimizing production).

The reasons for IC’s widespread use are clear:

  • Unmatched Versatility: IC tackles a vast array of ionic compounds, making it adaptable to a wide range of analytical needs.
  • Market-Specific Benefits: From ensuring regulatory compliance in environmental testing to safeguarding food and drug quality, to industrial process control in the petrochemical and chemical industrial complex, IC offers targeted solutions for various industries and a wide variety of sample types.
  • Superior Performance: With its high sensitivity and selectivity, IC can detect even trace levels of ions, providing accurate and reliable results.

Ensuring Reliable Quality Control with the
membraPure IONUS Ion Chromatograph

in quality control workflows, achieving consistent and reproducible results is paramount for reliable decision-making. The membraPure IONUS Ion Chromatograph excels in this area. Its exceptional precision boasts a standard deviation of less than 0.1%, as demonstrated in analyses of prepared Anion standards at 1 ppm.

This translates to highly dependable data, allowing you to confidently assess and ensure your samples meet defined quality requirements.

The membraPure IONUS Ion Chromatograph is a valuable tool for safeguarding the quality and purity of a vast variety of sample types. Chemical formulations often contain ionic compounds, including inorganic salts and charged molecules. The IONUS utilizes its exceptional separation capabilities to distinguish between these various ionic species, enabling researchers and quality control professionals to:

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Identify and quantify specific ions

The IONUS precisely identifies and measures the concentration of each ionic component within a sample.

Asses potential impurities

By effectively separating target ionic analytes in chemical compounds from unwanted contaminants, the IONUS helps ensure product purity and adherence to regulatory standards.

Monitor batch-to-batch consistency

The IONUS facilitates reliable and reproducible analyses, allowing manufacturers to maintain consistent quality throughout the production process.

Application 1: Environmental Analysis

Crucial Insights for Wastewater Treatment: IONUS Ion Chromatography Takes Center Stage

Effective wastewater treatment relies on a comprehensive understanding of its ionic composition. The membraPure IONUS Ion Chromatograph plays a critical role in this process.

This powerful analytical tool excels at separating and quantifying a broad spectrum of ions present in wastewater, including inorganic salts, heavy metals, and organic contaminants. This detailed analysis empowers wastewater treatment plants to:

  • Optimize Treatment Processes: By pinpointing the precise types and concentrations of ions, the IONUS allows for targeted treatment strategies, maximizing efficiency and resource utilization while reducing waste of treatment chemicals.
  • Ensure Regulatory Compliance: Stringent regulations govern wastewater discharge. The IONUS helps facilities meet these requirements by accurately monitoring key parameters like specific anions, heavy metals
  • Protect Environmental Health: The sensitive detection capabilities of the IONUS enable the identification of even trace levels of pollutants, safeguarding the health of our waterways and ecosystems.

The membraPure IONUS goes beyond basic ion measurement, providing crucial insights that are essential for responsible and effective wastewater management.

Determination of Anions in an Amine Solution
Determination of Anions in an Amine Solution Using the IONUS Ion Chromatograph Amine solutions are used in refinery boilers to prevent corrosion and scaling...

Determination of Anions in an Amine Solution Using the IONUS Ion Chromatograph

Amine solutions are vital in capturing carbon dioxide (CO2) from industrial flue gases. This captured CO2 can be utilized for various purposes, contributing to a more sustainable future. However, the efficiency of Amine-based CO2 capture can be significantly impacted by the presence of anion contaminants.

These anionic impurities, such as chloride and sulfate, can originate from the makeup water used in the capture process or from the degradation of the Amine itself. Therefore, monitoring and analyzing the concentration of anions in Amine solutions is crucial for maintaining optimal performance and ensuring the environmental sustainability of CO2 capture process.

Application 2: Boiler Corrosion Control

Optimizing Boiler Performance: IONUS Ensures Precise Measurement of Ionic Contaminants in Boiler Water

Maintaining optimal boiler water chemistry is crucial for safe and efficient operation. The membraPure IONUS Ion Chromatograph stands as a vital tool for power plants and industrial boiler facilities by providing accurate and reliable measurements of ionic contaminants.

Given the high pressures, temperatures, and aggressive water chemistry in power plant boilers, effective corrosion inhibition is crucial. A well-designed corrosion control program using a variety of chemical treatments, with corrosion inhibitors playing a key role in protecting boiler tubes, headers, drums, and other critical components from corrosion damage, should be regularly monitored. These corrosion inhibitors help minimize the harmful effects of dissolved oxygen, carbon dioxide, and other corrosive substances in the water-steam cycle.

The IONUS excels at separating and quantifying these ionic impurities, allowing for proactive monitoring and control of boiler water chemistry. Furthermore, the IONUS boasts an innovative automated cleaning system. Between analyses, the system can be programmed to automatically flush the separation column and suppressor. This ensures consistently low background noise, minimizes the risk of sample carryover and contamination and maintains reliable peak separation for every sample. This translates to dependable data, empowering operators to make informed decisions regarding water treatment strategies and ensure the safe and efficient operation of their boilers.

The IONUS Ion Chromatograph is well-positioned to provide accurate and reliable measurements of ionic contaminants, ionic control chemistries, volatile amines, and film-forming compounds to help in the control of the boiler chemistries. The IONUS can measure chloride, phosphate, sulfite, sulfate, thiocyanate, and thiosulfate. Cationic species include sodium, ammonium, potassium, magnesium, and calcium. Volatile amines include morpholine, diethanolamine, monoethanolamine, cyclohexylamine, and triethanolamine. IONUS can also be set up to measure several of the film-forming amines.

Refinery Boiler Control The Determination of DEA (Diethanolamine) in Refinery Boiler Water Systems Using the IONUS Ion Chromatograph

Alkanolamines, such as diethanolamine (DEA), are widely employed across various industries due to their versatile chemical properties. Their applications span from the production of consumer goods to critical industrial processes. In particular, the oil and gas industry heavily rely on alkanolamines for acid gas removal in refining and natural gas processing.

Boiler systems are critical components in industrial processes, particularly within refineries. Their efficient operation is paramount for maintaining production and minimizing downtime. A key aspect of boiler maintenance is water chemistry management, which significantly impacts boiler performance and longevity.

Determination of DEA (Diethanolamine) in Refinery Boiler Water Systems
The Determination of DEA (Diethanolamine) in Refinery Boiler Water Systems Using the IONUS Ion Chromatograph Alkanolamines, such as Diethanolamine...

Application 3: Air Quality Monitoring

Air quality is a critical concern for public health, workplace safety, and environmental sustainability. Our comprehensive Air Quality Monitoring Technical Note provides an in-depth exploration of advanced analytical techniques to measure hazardous airborne contaminants, informing industries, regulators, and researchers with important and relevant information to ensure cleaner and safer environments.

Employing the proven and reliable IONUS Ion Chromatograph with conductivity detection (IC-CDD), this report details precise methods for detecting a wide range of pollutants, from inorganic gases to organic acids. Whether you’re managing occupational exposure or assessing ambient air quality, this report is your essential guide to state-of-the-art monitoring solutions.

The report proves the versatility of the IONUS system, capable of analyzing 17 key analytes critical to air quality assessments. These include ammonia (NH₄⁺), hydrogen fluoride (HF), sulfuric acid (H₂SO₄), and nitrogen dioxide (NO₂), among others, as outlined in Table 1 inside the report. Each analyte is measured using standardized methods from leading authorities like NIOSH (National Institute for Occupational Safety and Health), OSHA (Occupational Safety and Health Administration), and KOSHA (Korea Occupational Safety and Health Agency). From KOSHA A-176-2019 for ammonia to OSHA ID-214 for ozone, the report aligns with globally recognized protocols, ensuring compliance and reliability across diverse applications.

Dive into the future of air quality monitoring with our free report! Packed with expert analysis, method comparisons, and real-world applications, this resource is a must-have for environmental scientists, safety officers, and policy makers. Download now to discover how the IONUS IC system addresses standardized methods that can simplify your approach to air quality, ensuring safer workplaces and healthier communities. Don’t miss this opportunity to stay ahead in the fight for cleaner air – get your copy today!

Air Quality Monitoring
Air Quality Monitoring Technical Note – membraPure IONUS Ion Chromatograph Optimal air quality is essential for both human health and a well-functioning...
Air Quality Monitoring

Our Air Quality Monitoring Technical Note is your essential resource for simplifying air quality analysis with the advanced IONUS Ion Chromatography system.

This comprehensive guide details methods for detecting 17 critical airborne contaminants, including ammonia, hydrogen fluoride, sulfuric acid, and nitrogen dioxide, using standardized protocols from NIOSH, OSHA, and KOSHA. From workplace safety to environmental compliance, the report provides clear, actionable insights into monitoring inorganic gases, organic acids, and reactive species, ensuring precision and reliability across diverse applications.

Discover how the IONUS system’s high-sensitivity IC-CDD technology provides the stability and versatility for reliable air quality assessments, supporting methods like NIOSH 6011 for halogens and OSHA ID-214 for ozone. Whether you’re an environmental scientist, safety officer, or regulator, this report equips you with the knowledge to tackle air quality challenges effectively.

Technical Notes

Demonstrating the IONUS Capability for Anion and Cation Analysis

Analytical assessments revealed that the limit of detection (LOD) and the limit of quantification (LOQ) are commonlyreported in pmol units, often without contextual connections to concentration levels or experimental conditions. The DIN 32645 method, a standard prevalent in German and European analytical frameworks but less recognized globally, has occasionally led to challenges in achieving universal understanding among stakeholders.

In contrast, the ICH method demonstrates greater international acceptance, enabling clearer communication across diverse technical audiences. To enhance accessibility and flexibility, we have adopted a dual-method approach, presenting data calculated using both DIN 32645 and ICH methodologies. This allows users to select the dataset that best aligns with their analytical preferences. Within the DIN framework, we have implemented two distinct determination techniques to ensure a thorough and comprehensive evaluation of results.

Scope

ICH Q2(R1)

DIN 32645

Objective

Validation of analytical methods in the pharmaceutical sector.

Definition and determination of detection, quantification, and determination limits in chemical analysis.

Definition of LOD

Smallest amount of an analyte that can be detected with acceptable certainty.

Smallest concentration of an analyte distinguishable from the blank value with a predefined statistical confidence.

Calculation Method

LOD = 3.3 × (σ/S), where σ is the standard deviation of the signal, and S is the slope of the calibration curve.

Uses the standard deviation of the blank value or the residuals from the calibration curve to calculate the detection limit.

Required Data

Multiple measurements of low-concentration samples to determine σ; calibration curve to determine S.

Measurements of blank samples and/or calibration standards; statistical evaluation to determine standard deviations and calibration function.

Scope of Application

Pharmaceutical analysis, particularly for validating quality control methods for drugs.

General chemical analysis, including environmental analysis and other fields requiring detection and quantification limits.

Statistical Basis

Based on the standard deviation of the signal and slope of the calibration curve; considers method precision.

Detailed statistical methods to determine detection, quantification, and determination limits; accounts for both systematic and random errors.

Practical Implementation

Requires creating a calibration curve in the low-concentration range and performing multiple measurements to calculate the standard deviation.

Involves detailed statistical tests, including variance homogeneity, linearity checks, and outlier detection.

Advantages

Relatively simple calculation; widely used in the pharmaceutical industry; tailored to drug analysis requirements.

Comprehensive and detailed methodology; applicable to a wide range of analytical procedures; provides clear definitions and statistical reliability.

Disadvantages

May lack detailed statistical assurance; designed specifically for pharmaceutical applications and may not directly apply to other fields.

More complex statistical requirements; requires extensive data collection and analysis; potentially more labor-intensive to implement.

Technical Note: Detection of Anions

Technical Note – Detection Limits – Anions – IONUS Ion Chromatograph The following data sheet presents the detection limits for anions. Based on...

Technical Note: Detection of Cations

Technical Note – Detection Limits – Cations – IONUS Ion Chromatograph The membraPURE IONUS team wanted to produce a Technical Note on the...

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Analysis of the amino acid composition of cell culture media
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